--- title: "Mayo's 3-Run Homer Lifts Orioles Over Yankees After Weathers Loses No-Hitter" description: "Coby Mayo's clutch blast in the late innings seals a critical AL East win for Baltimore." url: https://sportopod.com/en-US/cluster/mayo-s-3-run-homer-lifts-orioles-over-yankees-after-weathers-mp25cxo5 published: 2026-05-16T02:43:35.537601+00:00 updated: 2026-05-16T14:03:16.481087+00:00 author: "Kostadin Stamboliev" publisher: "Pineido" site: "Sportopod" language: en topics: ["baseball"] --- # Mayo's 3-Run Homer Lifts Orioles Over Yankees After Weathers Loses No-Hitter > Coby Mayo's clutch blast in the late innings seals a critical AL East win for Baltimore. The Baltimore Orioles took a pivotal AL East clash against the New York Yankees, powered by a dramatic three-run homer from Coby Mayo. The game was defined by Orioles starter Ryan Weathers' near-historic performance, as he carried a no-hitter into the seventh inning before a single broke it up. Yankees reliever Brent Headrick then surrendered the decisive blast to Mayo, shifting the momentum and sealing the win for Baltimore. Weathers was electric, dominating the Yankees lineup with precision and poise. He retired the first 18 batters he faced, striking out seven and walking none, before a soft single in the seventh ended his no-hit bid. It was a career-defining outing for the young pitcher, showcasing the depth of the Orioles' pitching staff. Despite the broken no-hitter, Weathers left the game with a lead, setting the stage for Mayo's heroics. Mayo's home run came in the eighth inning, a towering shot to left field that silenced the Yankee Stadium crowd. The blast not only gave the Orioles a commanding lead but also underscored the team's ability to deliver in high-pressure moments. For the Yankees, the loss stings, as they squandered a chance to gain ground in the tightly contested AL East. This win is more than a single game; it's a statement. The Orioles proved they can hang with the division's best, blending stellar pitching with timely hitting. As the playoff race heats up, performances like Weathers' and Mayo's could be the difference between October baseball and an early vacation. What's next: The Orioles look to build on this momentum in the series finale, while the Yankees will aim to bounce back and avoid falling further behind in the division. ## Why this matters This isn't just another game; it's a statement win for the Baltimore Orioles against their fierce AL East rivals, the New York Yankees. Ryan Weathers' near no-hitter showcases the depth and potential of the Orioles' pitching staff, while Coby Mayo's clutch home run highlights the team's ability to deliver under pressure. Wins like this are pivotal in a tight divisional race, boosting morale and potentially impacting playoff positioning down the stretch. It proves the O's are legit contenders. ## Frequently asked ### Who hit the game-winning home run for the Orioles? Coby Mayo hit a three-run homer in the eighth inning off Yankees reliever Brent Headrick to secure the win. ### How close was Ryan Weathers to a no-hitter? Weathers carried a no-hitter into the seventh inning before allowing a single. He retired the first 18 batters and finished with seven strikeouts. ### What does this win mean for the Orioles' playoff chances? It's a crucial victory in a tight AL East race, boosting morale and proving the Orioles can compete with top teams like the Yankees. ### Who lost the no-hitter for the Yankees? The Yankees didn't lose a no-hitter; Orioles pitcher Ryan Weathers lost his no-hit bid when a Yankee broke it up with a single in the seventh. ## Sources & Citations - [Mayo's 3-run homer lifts Orioles over Yankees after Weathers loses no-hitter](https://www.sportsnet.ca/mlb/article/mayos-3-run-homer-lifts-orioles-over-yankees-after-weathers-loses-no-hitter/) — TheNewsAPI.com (2026-05-12) --- Cite: Mayo's 3-Run Homer Lifts Orioles Over Yankees After Weathers Loses No-Hitter. Sportopod, 2026-05-16. https://sportopod.com/en-US/cluster/mayo-s-3-run-homer-lifts-orioles-over-yankees-after-weathers-mp25cxo5